Publications

Fernández Zapata C, Giacomello G, Spruth EJ, Middeldorp J, Gallaccio G, Dehlinger A, Dames C, Leman JKH, van Dijk RE, Meisel A, Schlickeiser S, Kunkel D, Hol EM, Paul F, Parr MK, Priller J, and Böttcher C: Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer’s disease. Nat Commun 13: 7210, doi: 10.1038/s41467-022-34719-2 (2022).

Ferrarese R, […], Prinz M, Pelicci G, Kammerer B, Boerries M, Carro MS: ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma. Glia, doi: 10.1002/glia.24299 (2022).

Carvalho LAR, Ross B, Fehr L, Bolgi O, Wöhrle S, Lum KM, Podlesainski D, Vieira AC, Kiefersauer R, Félix R, Rodrigues T, Lucas SD, Groß O, Geiss-Friedlander R, Cravatt BF, Huber R, Kaiser M, Moreira R: Chemoproteomics-Enabled Identification of 4-Oxo-β-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angew Chem Int Ed Engl 61(47), e202210498, doi: 10.1002/anie.202210498 (2022).

Locatelli G, Marques-Ferreira F, Katsoulas A, […] Prinz M, Tresch A, Becher B, Buch T: IGF1R expression by adult oligodendrocytes is not required in the steady-state but supports neuroinflammation. Glia, doi: 10.1002/glia.24299 (2022).

Paolicelli RC, Sierra A, Stevens B, [..] Amit I, […] Jung, S, […] Priller J, Prinz M, […] Wyss-Coray T: Microglia states and nomenclature: A field at its crossroads. Neuron 110(21), 3458-3483, doi: 10.1016/j.neuron.2022.10.020 (2022).

Jarick KJ, Topczewska PM, Jakob MO, Yano H, Arifuzzaman M, Gao X, Boulekou S, Stokic-Trtica V, Leclère PS, Preußer A, Rompe ZA, Stamm A, Tsou AM, Chu C, Heinrich FR, Guerra GM, Durek P, Ivanov A, Beule D, Helfrich S, Duerr CU, Kühl AA, Stehle C, Romagnani C, Mashreghi MF, Diefenbach A, Artis D, Klose CSN: Non-redundant functions of group 2 innate lymphoid cells. Nature 611(7937), 794-800, doi: 10.1038/s41586-022-05395-5 (2022).

Tsou AM, Yano H, Parkhurst CN, Mahlakõiv T, Chu C, Zhang W, He Z, Jarick KJ, Zhong C, Putzel GG, Hatazaki M; JRI IBD Live Cell Bank Consortium, Lorenz IC, Andrew D, Balderes P, Klose CSN, Lira SA, Artis D: Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces. Nature 611(7937), 787-793. doi: 10.1038/s41586-022-05297-6 (2022).

Hettwer J, Hinterdobler J, Miritsch B, Deutsch MA, Li X, Mauersberger C, Moggio A, Braster Q, Gram H, Robertson AAB, Cooper MA, Groß O, Krane M, Weber C, Koenig W, Soehnlein O, Adamstein NH, Ridker P, Schunkert H, Libby P, Kessler T, Sager HB: Interleukin-1β suppression dampens inflammatory leucocyte production and uptake in atherosclerosis. Cardiovasc Res 118(13):2778-2791. doi: 10.1093/cvr/cvab337 (2022).

Cook J and Prinz M: Regulation of microglial physiology by the microbiota. Gut Microbes 14(1):2125739, doi: 10.1080/19490976.2022.2125739 (2022).

Ho JNHG, Schmidt D, Lowinus T, […] Zeiser R: Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood 140(10), 1167-1181, doi: 10.1182/blood.2022016082 (2022).

Hasavci D, Blank T: Age-dependent effects of gut microbiota metabolites on brain resident macrophages. Front Cell Neurosci 16:944526; doi: 10.3389/fncel.2022.944526 (2022).

Letizia M, Wang Y-H, Kaufmann U, Gerbeth L, Sand A, Brunkhorst M, Weidner P, Ziegler JF, Böttcher C, Schlickeiser S, Fernández C, Yamashita M, Stauderman K, Sun K, Kunkel D, Prakriya M, IBDome Researchers; Sanders AD, Siegmund B, Feske S, Weidinger C: Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease. EMBO Mol Med e15687, doi: 10.15252/emmm.202215687 (2022).

Aktories P, Petry P, Glatz P, Andrieux G, Oschwald A, Botterer H, Gorka O, Erny D, Boerries M, Henneke P, Groß O, Prinz M, Kierdorf K: An improved organotypic cell culture system to study tissue-resident macrophages ex vivo. Cell Reports Methods, https://doi.org/10.1016/j.crmeth.2022.100260 (2022).

Mihlan M, Safaiyan S, Stecher M, Paterson N, and Lämmermann T: Surprises from Intravital Imaging of the Innate Immune Response. Annu Rev Cell Dev Biol, doi: 10.1146/annurev-cellbio-120420-112849 (2022).

Grüninger PK, Uhl F, Herzog H, Gentile G, Andrade-Martinez M, Schmidt T, Han K, Morgens DW, Bassik MC, Cleary ML, Gorka O, Zeiser R, Groß O, Duque-Afonso J. Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia. Cancer Gene Ther 29(11):1751-1760. doi: 10.1038/s41417-022-00491-0 (2022).

Haring E, Andrieux G, Uhl FM, Krausz M, Proietti M, Sauer B, Esser PR, Martin SF, Pfeifer D, Schmitt-Graeff A, Duyster J, Köhler N, Grimbacher B, Boerries M, Aumann K, Zeiser R, and Apostolova P: Therapeutic targeting of endoplasmic reticulum stress in acute graft- versus-host disease . Haematologica 107(7), 1538-1554, doi: 10.3324/haematol.2021.278387 (2022).