Publications

Wenger V, Garcia-Manero G, Zeiser R, Lübbert M: DNA methyltransferase inhibitors in hematological malignancies and solid tumors. Int J Cancer 158(2):433–461; doi: 10.1002/ijc.70197 (2025).

Zähringer A, Vinnakota JM, Wertheimer T, Saalfrank P, Follo M, Ingelfinger F, Zeiser R: AIstain: Enhancing microglial phagocytosis analysis through deep learning. Cell Rep Methods 5(11):101207. doi: 10.1016/j.crmeth.2025.101207 (2025).

Gres V, Göcer M, Kolter J, Henneke P: Trained immunity in skin infections: Macrophages and beyond. eLife 14:e106688; doi: 10.7554/eLife.106688 (2025).

Ullrich Gavilanes EM, Bartos LM, Gernert JA, Carral CA, Navarro DR, Havla J, Gerdes L-A, Gnörich JS, Kunze LH, Dorneich JS, Pakula V, Tagnin L, Zimmermann H, Seelos K, Franzmeier N, Frontzkowski L, Pedrosa de Barros N, Ribbens A, Zwergal RM, Zwergal A, Vollmar C, Remi J, Picon C, Reynolds R, Merkler D, Wattjes MP, Kümpfel T, Brendel M, Kerschensteiner M: SV2A-PET imaging uncovers cortical synapse loss in multiple sclerosis. Sci Transl Med 17(818):eadt5585; doi: 10.1126/scitranslmed.adt5585 (2025).

Petry P, Oschwald A, Merkt S, Dinh TLJ, Andrieux G, Crisand C, Botterer H, Nent E, Paterson N, Havermans M, Sankowski R, Schilling O, Boerries M, Amann L, Groß O, Schlitzer A, Prinz M, Lämmermann T, Kierdorf K: Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface. Dev Cell S1534-5807(25)00532-5. doi: 10.1016/j.devcel.2025.08.012 (2025).

Kelm N, Kespohl M, Borowski S, Ochs S, Knobeloch K-P, Huis In ‘t Veld LGM, Klingel K, Beling A: Enhanced ISGylation via USP18 Isopeptidase Inactivation Fails to Mitigate the Inflammatory or Functional Course of Coxsackievirus B3-Induced Myocarditis. Cell Physiol Biochem 59(S3):1-21; doi: 10.33594/000000811 (2025).

Kolter J, Döring CL, Sarout S, Baasch S, Steele L, Alsumati R, Silva GVL, Silva CEA, Marques Paiva I, Mansoori Moghadam Z, Gres V, Lohrmann F, Aktories P, Buchegger T, Bijnen M, Doumard L, Voisin B, Le Foll C, Lachmann N, Greter M, Kierdorf K, Haniffa M, Cunha TM, Flacher V, Henneke H: Sensory neurons shape local macrophage identity via TGF-β signaling. Immunity S1074-7613(25)00367-X; doi: 10.1016/j.immuni.2025.08.004 (2025).

Braun LM, Lu Y, Zeiser R: Clinical perspective and treatment of immune-related colitis after cancer immunotherapy. Trends Cancer 11(11):1058-1077; doi: 10.1016/j.trecan.2025.07.005 (2025).

Frosch M, Shimizu T, Wogram E, Amann L, Gruber L, Groisman AI, Fliegauf M, Schwabenland M, Chhatbar C, Zechel S, Rosewich H, Gärtner J, Quintana FJ, Buescher JM, Blank T, Binder H, Stadelmann C, Letzkus JJ, Hopf C, Masuda T, Knobeloch K-P & Prinz M: Microglia–neuron crosstalk via Hex–GM2– MGL2 maintains brain homeostasis. Nature; doi: 10.1038/s41586-025-09477-y (2025).

Eckert P, Nöller M, Müller M, Haas R, Ruf J, Franz H, Moos K, Yu J-A, Zhao D, Xie W, Boerries M, Walz G, Yakulov TA: Targeting GLP-1 Signaling Ameliorates Cystogenesis in a Zebrafish Model of Nephronophthisis.
Int J Mol Sci 26(15):7366; doi: 10.3390/ijms26157366 (2025).

Zähringer A, Vinnakota JM, Wertheimer T, Follo M, Zeiser R: Protocol for performing and analyzing a live-cell imaging-based microglia phagocytosis assay using AI on the Olympus ScanR system. STAR Protoc 6(3):103846; doi: 10.1016/j.xpro.2025.103846 (2025).

Sheban F, San Phan T, Xie K, Ingelfinger F, Gur C, Shapir Itai Y, Blecher-Gonen R, Yu C, Avellino R, Chalan P, Freitag K, Yofe I, Yutkin V, Boyeau P, Ergen C, Hong J, Mazuz K, Liu Y, Chen K, Dahan R, Kortylewski M, Yosef N, Weiner A, Amit I: ZEB2 is a master switch controlling the tumor-associated macrophage program. Cancer Cell 43(7):1227-1241.e11; doi: 10.1016/j.ccell.2025.03.021 (2025).

Ardura-Fabregat A, Bosch LFP, Wogram E, Mossad O, Sankowski R, Aktories P, Kieger L, Cook J, Hasavci D, Ulupinar H, Brock D, Wang F, Iovino N, Wald S, Preissl S, Yilmaz B, Schnepf D, Macpherson AJ, Blank T, Kierdorf K, Prinz M: Response of spatially defined microglia states with distinct chromatin accessibility in a mouse model of Alzheimer’s disease. Nat Neurosci; doi: 10.1038/s41593-025-02006-0 (2025).

Chatterjee S, Rückert T, Martin I, Michaeli E, Buescher J, Apostolova P, Erny D, Lalioti ME, Biavasco F, Hartmann A, Runge S, Braun LM, Talvard-Balland N, Adams RC, Schmitt-Graeff A, Cook J, Wenger V, Athanassopoulos D, Hasavci D, Vallejo-Janeta AP, Blank T, Schaible P, Vinnakota JM, Zähringer A, Ganal-Vonarburg SC, Melchinger W, Pfeifer D, Köhler N, Rosshart SP, Michonneau D, Socié G, Andrieux G, Cabezas-Wallscheid N, Boerries M, Prinz M, Zeiser R. Gut microbiota-derived TMAVA is a modulator of acute CNS-GVHD. J Exp Med 222(9):e20242180; doi: 10.1084/jem.20242180 (2025).

Lu H, Diaz-Pier S, Lenz M, Vlachos A: The interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks. eLife 12:RP88376; doi: 10.7554/eLife.88376 (2025).

Seidl M, Bavafaye Haghighi E, Lösslein AK, Hufnagel M, Lohrmann F, Schneider C, Kohlfürst DS, Zenz W, Gorkiewicz G, Feiterna-Sperling C, Krüger R, Bronsert P, Neppl C, Sommer KZ, Stehl V, Boerries M, Kuntz M, Henneke P: Immunopathogenic and clinical implications of advanced tissue analysis in non-tuberculous mycobacterial infections in children. Front Immunol 16:1597074; doi: 10.3389/fimmu.2025.1597074 (2025).