Publications

Mass E, Nimmerjahn F, Kierdorf K and Schlitzer A.Tissue-specific macrophages: how they develop and choreograph tissue biology. Nat Rev Immunol 1–17; doi: 10.1038/s41577-023-00848-y (2023).

Amann L, Masuda T, Prinz M: Mechanisms of myeloid cell entry to the healthy and diseased central nervous system. Nat Immunol 24(3):393-407; doi: 10.1038/s41590-022-01415-8 (2023).

De Schepper S, Ge JZ, Crowley G, Ferreira LSS, Garceau D, Toomey CE, Sokolova D, Rueda-Carrasco J, Shin S-H, Kim J-S, Childs T, Lashley T, Burden JJ, Sasner M, Frigerio CS, Jung S, Hong S: Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease. Nat Neurosci 26(3): 406–415; doi: 10.1038/s41593-023-01257-z (2023).

Griewahn L, Müller-Foxworth M, Peintner L, Wissler M, Weiss M, Brauns-Schubert P, Massoumi R, Borner C, Groß O, Yabal M, Charvet C, Maurer U: SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD. Cell Rep 42(1):111961; doi: 10.1016/j.celrep.2022.111961 (2023).

Thelen B, Schipperges V, Knörlein P, Hummel JF, Arnold F, Kupferschmid L, Klose CSN, Arnold SJ, Boerries M, Tanriver Y: Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4+ T cells. Front Immunol 14:1058267; doi: 10.3389/fimmu.2023.1058267 (2023).

Neuwirt E, Magnani G, Ćiković T, Wöhrle S, Fischer L, Kostina A, Flemming S, Fischenich NJ, Saller BS, Gorka O, Renner S, Agarinis C, Parker CN, Boettcher A, Farady CJ, Kesselring R, Berlin C, Backofen R, Rodriguez-Franco M, Kreutz C, Prinz M, Tholen M, Reinheckel T, Ott T, Groß CJ, Jost PJ, Groß O: Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis. Sci Signal 16(768):eabh1083; doi: 10.1126/scisignal.abh1083 (2023).

Giacomello G, Otto C, Priller J, Ruprecht K, Böttcher C, Parr MK: 1,2-13C2-Glucose Tracing Approach to Assess Metabolic Alterations of Human Monocytes under Neuroinflammatory Conditions. Curr Issues Mol Biol 45(1):765-781; doi: 10.3390/cimb45010051 (2023).

Wallach T, Raden M, Hinkelmann L, Brehm M, Rabsch D, Weidling H, Krüger C, Kettenmann H, Backofen R, Lehnardt S: Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia. Front Immunol, 13; doi.org/10.3389/fimmu.2022.1066456 (2023).

Faust TE, Feinberg PA, O’Connor C, Kawaguchi R, Chan A, Strasburger H, Masuda T, Amann L, Knobeloch KP, Prinz M, Schaefer A and Schafer DP: A comparative analysis of microglial inducible Cre lines. bioRxiv; doi: 10.1101/2023.01.09.523268 (2023).

Rapp J, Jung M, Klar RFU, Wolf J, Arnold J, Gorka O, Groß O, Lange C, Agostini H, Schlunck G, Bucher F: STAT3 signaling induced by the IL-6 family of cytokines modulates angiogenesis. J Cell Sci 136(1):jcs260182; doi: 10.1242/jcs.260182 (2023).

McNamara, NB, Munro, DAD, Bestard-Cuche, N, Uyeda, A, Bogie, JFJ, Hoffmann, A, Holloway, RK, Molina-Gonzalez, I, Askew, KE, Mitchell, S, Mungall, W, Dodds, M, Dittmayer, C, Moss, J, Rose, J, Szymkowiak, S, Amann, L, McColl, BW, Prinz, M, Spires-Jones, TL, Stenzel, W, Horsburgh, K, Hendriks, JJA, Pridans, C, Muramatsu, R, Williams, A, Priller, J*, & Miron, VE*. Microglia regulate central nervous system myelin growth and integrity. Nature, 613(7942):120-129. https://doi: 10.1038/s41586-022-05534-y (2023).

Haimon Z, Frumer GR, Kim J-S, Trzebanski S, Haffner-Krausz R, Ben-Dor S, Porat Z, Muschaweckh A, Chappell-Maor L, Boura-Halfon S, Korn T & Jung S: Cognate microglia–T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology. Nature Immunology, https://doi.org/10.1038/s41590-022-01360-6 (2022).

Fernández Zapata C, Giacomello G, Spruth EJ, Middeldorp J, Gallaccio G, Dehlinger A, Dames C, Leman JKH, van Dijk RE, Meisel A, Schlickeiser S, Kunkel D, Hol EM, Paul F, Parr MK, Priller J, and Böttcher C: Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer’s disease. Nat Commun 13: 7210, doi: 10.1038/s41467-022-34719-2 (2022).

Ferrarese R, […], Prinz M, Pelicci G, Kammerer B, Boerries M, Carro MS: ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma. Glia, doi: 10.1002/glia.24299 (2022).

Carvalho LAR, Ross B, Fehr L, Bolgi O, Wöhrle S, Lum KM, Podlesainski D, Vieira AC, Kiefersauer R, Félix R, Rodrigues T, Lucas SD, Groß O, Geiss-Friedlander R, Cravatt BF, Huber R, Kaiser M, Moreira R: Chemoproteomics-Enabled Identification of 4-Oxo-β-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9. Angew Chem Int Ed Engl 61(47), e202210498, doi: 10.1002/anie.202210498 (2022).

Locatelli G, Marques-Ferreira F, Katsoulas A, […] Prinz M, Tresch A, Becher B, Buch T: IGF1R expression by adult oligodendrocytes is not required in the steady-state but supports neuroinflammation. Glia, doi: 10.1002/glia.24299 (2022).