Publications

Biniaris-Georgallis S-I, Aschman T, Stergioula K, Schreiber F, Jafari V, Taranko A, Karmalkar T, Kasapi A, Rovis TL, Jelencic V, Bejarano DA, Fabry L, Papacharalampous M, Mattiola I, Molgora M, Hou J, Hublitz KW, Heinrich F, Guerra GM, Durek P, Patone G, Lindberg EL, Maatz H, Hölsken O, … Triantafyllopoulou A: Amplification of autoimmune organ damage by NKp46-activated ILC1s. Nature 634(8035):952-960; doi: 10.1038/s41586-024-07907-x (2024).

Topczewska PM, Savvopoulou A, Cosovanu C, Klose CSN: Transcriptional profiling identifies IL-33-expressing intestinal stromal cells as a signaling hub poised to interact with enteric neurons.
Front Cell Dev Biol 12:1420313; doi: 10.3389/fcell.2024.1420313 (2024).

Wenger V, Zeiser R: Deciphering the role of the major histocompatibility complex, the intestinal microbiome and metabolites in the pathogenesis of acute graft-versus-host disease. Best Pract Res Clin Haematol 37(3):101567; doi: 10.1016/j.beha.2024.101567 (2024).

Zimmermann JA, Lucht K, Stecher M, Badhan C, Glaser KM, Epple MW, Koch LR, Deboutte W, Manke T, Ebnet K, Brinkmann F, Fehler O, Vogl T, Schuster E-M, Bremser A, Buescher JM, Rambold AS: Functional multi-organelle units control inflammatory lipid metabolism of macrophages. Nat Cell Biol 26(8):1261-1273; doi: 10.1038/s41556-024-01457-0 (2024).

Rosmus D-D, Koch J, Hausmann A, Chiot A, Arnhold F, Masuda T, Kierdorf K, Marie S, Kuhrt H, Fröba J, Wolf J,
Boneva S, Gericke M, Ajami B, Prinz M, Lange C and Wieghofer P: Redefining the ontogeny of hyalocytes as yolk sac‑derived tissue‑resident macrophages of the vitreous body. J Neuroinflammation 21:168; doi: 10.1186/s12974-024-03110-x (2024).

Moeed A, Thilmany N, Beck F, Puthussery BK, Ortmann N, Haimovici A, Badr MT, Haghighi EB, Boerries M, Öllinger R, Rad R, Kirschnek S, Gentle IE, Donakonda S, Petric PP, Hummel JF, Pfaffendorf E, Zanetta P, Schell C Schwemmle M, Weber A, Häcker G: The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection. Cell Death Differ 31(7):924-937; doi: 10.1038/s41418-024-01320-7 (2024).

Colcerasa A, Friedrich F, Melesina J, Moser P, Vogelmann A, Tzortzoglou P, Neuwirt E, Sum M, Robaa D, Zhang L, Ramos-Morales E, Romier C, Einsle O, Metzger E, Schüle R, Groß O, Sippl W, Jung M: Structure-Activity Studies of 1,2,4-Oxadiazoles for the Inhibition of the NAD+-Dependent Lysine Deacylase Sirtuin 2. J Med Chem 67(12):10076-10095; doi: 10.1021/acs.jmedchem.4c00229 (2024).

Talvard-Balland N, Braun LM, Dixon KO, Zwick M, Engel H, Hartmann A, Duquesne S, Penter L, Andrieux G, Rindlisbacher L, Acerbis A, Ehmann J, Köllerer C, Ansuinelli M, Rettig A, Moschallski K, Apostolova P, Brummer T, Illert AL, Schramm MA, Cheng Y, Köttgen A, Duyster Y, Menssen HD, Ritz J, Blazar BR, Boerries M, Schmitt-Gräff A, Sariipek N, Van Galen N, Buescher JM, Cabezas-Wallscheid N, Pahl HL, Pearce EL, Soiffer EJ, Wu CJ, Vago L, Becher B, Köhler N, Wertheimer T,Kuchroo VK, and Zeiser R: Oncogene-induced TIM-3 ligand expression dictates susceptibility to anti–TIM-3 therapy in mice. J Clin Invest 134(16):e177460; doi: 10.1172/JCI177460 (2024).

Petry P, Aktories P, Oschwald A, Kierdorf K: Protocol for long-term monocultures of murine macrophages derived from distinct adult tissues. STAR Protoc 5(3):103145; doi: 10.1016/j.xpro.2024.103145 (2024).

Munro DAD, Bestard-Cuche N, McQuaid C, Chagnot A, Shabestari SK, Chadarevian JP, Maheshwari U, Szymkowiak S, Morris K, Mohammad M, Corsinotti A, Bradford B, Mabbott N, Lennen RJ, Jansen MA, Pridans C, McColl BW, Keller A, Blurton-Jones M, Montagne A, Williams A, Priller J: Microglia protect against age-associated brain pathologies. Neuron S0896-6273(24)00365-9; doi: 10.1016/j.neuron.2024.05.018 (2024).

Vinnakota JM, Adams RC, Athanassopoulos D, Schmidt D, Biavasco F, Zähringer A, Erny D, Schwabenland M, Langenbach M, Wenger V, Salié H, Cook J, Mossad O, Andrieux G, Dersch R, Rauer S, Duquesne S, Monaco G, Wolf P, Blank T, Häne P, Greter M, Becher B, Henneke P, Pfeifer D, Blazar BR, Duyster J, Boerries M, Köhler N, Chhatbar CM, Bengsch B, PrinzM, Zeiser R: Anti-PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation. Sci Transl Med 16(751):eadj9672; doi: 10.1126/scitranslmed.adj9672 (2024).

Trzebanski S, Kim JS, Larossi N, Raanan A, Kancheva D, Bastos J, Haddad M, Solomon A, Sivan E, Aizik D, Sekeresova Kralova J, Gross-Vered M, Boura-Halfon S, Lapidot T, Alon R, Movahedi K, Jung S: Classical monocyte ontogeny dictates their functions and fates as tissue macrophages. Immunity 57(6):1225-1242.e6; doi: 10.1016/j.immuni.2024.04.019 (2024).

Kessler S, Burke B, Andrieux G, Schinköthe J, Hamberger L, Kacza J,Zhan S, Reasoner C, Dutt TS, Kaukab Osman M, Henao-Tamayo M, Staniek J, Villena Ossa JF, Frank DT, Ma W, Ulrich R, Cathomen T, Boerries M, Rizzi M, Beer M, Schwemmle M, Reuther P, Schountz T, and Ciminski K: Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level. Nat Commun 15(1):4500; doi: 10.1038/s41467-024-48934-6 (2024).

Bredow C, Thery F, Wirth EK, Ochs S, Kespohl M, Kleinau G, Kelm N, Gimber N, Schmoranzer J, Voss M, Klingel K, Spranger J, Renko K, Ralser M, Mülleder M, Heuser A, Knobeloch KP, Scheerer P, Kirwan J, Brüning U, Berndt N, Impens F, Beling A: ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection . Cardiovasc Res 120(6):644-657; doi: 10.1093/cvr/cvae026 (2024).

Röwekamp I, Maschirow L, Rabes A, Fiocca Vernengo F, Hamann L, Heinz GA, Mashreghi MF, Caesar S, Milek M, Fagundes Fonseca AC, Wienhold SM, Nouailles G, Yao L, Mousavi S, Bruder D, Boehme JD, Puzianowska-Kuznicka M, Beule D, Witzenrath M; CAPNETZ Study Group; Löhning M, Klose CSN, Heimesaat MM, Diefenbach A, Opitz B: IL-33 controls IL-22-dependent antibacterial defense by modulating the microbiota. Proc Natl Acad Sci U S A 121(22):e2310864121; doi: 10.1073/pnas.2310864121 (2024).

Surala M, Soso-Zdravkovic L, Munro D, Rifat A, Ouk K, Vida I, Priller J, Madry C: Lifelong absence of microglia alters hippocampal glutamatergic networks but not synapse and spine density. EMBO Rep 25(5):2348-2374; doi: 10.1038/s44319-024-00130-9 (2024).