Publications

Hamarsheh S, Osswald L, Saller BS, Unger S, De Feo D, Vinnakota JM, Konantz M, Uhl FM, Becker H, Lübbert M, Shoumariyeh K, Schürch C, Andrieux G, Venhoff N, Schmitt-Graeff A, Duquesne S, Pfeifer D, Cooper MA, Lengerke C, Boerries M, Duyster J, Niemeyer CM, Erlacher M, Blazar BR, Becher B, Groß O, Brummer T and Zeiser R: Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation. Nature Communications 11, 1659 (2020).

Duscha A, Gisevius B, Hirschberg S, Yissachar N, Stangl GI, Eilers E, Bader V, Haase S, Kaisler J, David C, Schneider R, Troisi R, Zent D, Hegelmaier T, Dokalis N, Gerstein S, Del Mare-Roumani S, Amidror S, Staszewski O, Poschmann G, Stühler K, Hirche F, Balogh A, Kempa S, Träger P, Zaiss MM, Holm JB, Massa MG, Nielsen HB, Faissner A, Lukas C, Gatermann SG, Scholz M, Przuntek H, Prinz M, Forslund SK, Winklhofer KF, Müller DN, Linker RA, Gold R, Haghikia A: Propionic acid shapes the multiple sclerosis disease course by an immunomodulatory mechanism. Cell,  180(6),1067-1080.e16 8 (2020).

Erny D, Prinz M: How microbiota shape microglial phenotypes and epigenetics. Glia 68(8), 1655-1672. doi: 10.1002/glia.23822 (2020).

Marschner D, Falk M, Javorniczky NR, Hanke-Müller K, Rawluk J, Schmitt-Graeff A, Simonetta F, Haring E, Dicks S, Ku M, Duquesne S, Aumann K, Rafei-Shamsabadi D, Meiss F, Marschner P, Boerries M, Negrin RS, Duyster J, Zeiser R, and Köhler N: MicroRNA-146a regulates immune-related adverse events caused by immune checkpoint inhibitors. JCI Insight 5(6), e132334 (2020).

Hotter B, Hoffmann S, Ulm L, Montaner J, Bustamante A, Meisel C, Meisel A: Inflammatory and stress markers predicting pneumonia, outcome, and etiology in patients with stroke. Biomarkers for predicting pneumonia, functional outcome, and death after stroke. Neurol Neuroimmunol Neuroinflamm 7(3): e692, doi: 10.1212/NXI.0000000000000692 (2020).

Kierdorf K, Hersperger F, Sharrock J, Vincent CM, Ustaoglu P, Dou J, Gyoergy A, Groß O, Siekhaus DE, Dionne MS: Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila. Elife 9. pii: e51595 (2020).

Wallach T, Wetzel M, Dembny P, Staszewski O, Krüger C, Buonfiglioli A, Prinz M, Lehnardt S: Identification of CNS injury-related microRNAs as novel Toll-like Receptor 7/8 signaling ctivators by Small RNA Sequencing. Cells 9(1), pii: E186 (2020).

Kolter J, Kierdorf K, Henneke P: Origin and Differentiation of Nerve-Associated Macrophages. J Immunol 204, 271-289; doi: 10.4049/jimmunol.org/content/204/2/271 (2020).

Bell OH, Copland DA, AWard A, Nicholson LB, Lange CAK,Chu CJ and Dick AD: Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation. Front Immunol 10 (3033), doi: 10.3389/fimmu.2019.03033 (2020).

Böttcher C, Fernández-Zapata C, Schlickeiser S, Kunkel D, Schulz AR, Mei HE, Weidinger C, Gieß RM, Asseyer S, Siegmund B, Paul F, Ruprecht K, Priller J: Multi-parameter immune profiling of peripheral blood mononuclear cells by multiplexed single-cell mass cytometry in patients with early multiple sclerosis. Sci Rep 9(1), 19471. doi: 10.1038/s41598-019-55852-x 8 (2019).

Sankowski R, Strohl JJ, Huerta TS, Nasiri E, Mazzarello AN, D’Abramo C, Cheng KF, Staszewski O, Prinz M, Huerta PT, and Al-Abed Y: Endogenous retroviruses are associated with hippocampus-based memory impairment. PNAS 116 (51) 25982-25990; doi.org/10.1073/pnas.182216411 (2019).

R Mathew N, Vinnakota JM, Apostolova P, Erny D, Hamarsheh S, Andrieux G, Kim JS, Hanke K, Goldmann T, Chappell-Maor L, El-Khawanky N, Ihorst G, Schmidt D, Duyster J, Finke J, Blank T, Boerries M, Blazar BR, Jung S, Prinz M, Zeiser R: Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia. J Clin Invest, pii: 130272; doi: 10.1172/JCI130272 (2019).

Geirsdottir L, David E, Keren-Shaul H, Weiner A, Bohlen SC,  Neuber J, Balic A, Giladi A, Sheban F, Dutertre CA, Pfeifle C, Peri F, Raffo-Romero A, Vizioli J, Matiasek K, Scheiwe C, Meckel S, Mätz-Rensing K, van der Meer F, Thormodsson FR, Stadelmann C, Zilkha N, Kimchi T, Ginhoux F, Ulitsky I, Erny D, Amit I, Prinz M: Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program. Cell 179 (7), 1609-1622.e16; doi: 10.1016/j.cell.2019.11.010 (2019).

Ben-Yehuda H, Matcovitch-Natan O, Kertser A, Spinrad A, Prinz M, Amit I and Schwartz M: Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress. Mol Psychiatry; doi: 10.1038/s41380-019-0604-0 (2019).