Publications

Kim J-S, Trzebanski S, Shin S-H, Schori L, Frumer Friedman GR, Noa Chapal Ilani NC, Kadam A, Vicario R, Aust O, Bugaeva P, Piatek S, Ismajli LK, Hoffmann CJ, Scheller M, Boura-Halfon S, Kaushansky N, Golani O, Solomon A, Liu Z, Amann L, Böhm-Sturm P, Koch SP, Wenger N, Netherlands Brain Bank, Ginhoux F, Prinz M, Avraham R, Harms C, Geissmann F, Müller-Tidow C, Uderhardt S, Milenkovic I, Shlush L, Jung S: Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice . Cell Rep 44(5):115609; doi: 10.1016/j.celrep.2025.115609 (2025).

Frosch M & Prinz M: Niche-specific therapeutic targeting of myeloid cells in the central nervous system . Immunity 58(5):1101-1119; doi: 10.1016/j.immuni.2025.03.016 (2025).

Wang M, Otto C, Fernández Zapata C, Dehlinger A, Gallaccio G, Diekmann LM, Niederschweiberer M, Schindler P, Körtvélyessy P, Kunkel D, Paul F, Ruprecht K, Böttcher C. Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics. iScience. iScience 28(5):112383; doi: 10.1016/j.isci.2025.112383 (2025).

Zähringer A, Morgado I, Erny D, Ingelfinger F, Gawron J, Chatterjee S, Wenger V, Schmidt D, Schwöbel LF, Adams RC, Langenbach M, Hartmann A, Osswald N, Wolf J, Schlunck G, Briquez PS, Grueter K, Ruess DA, Frew I, Burk A-C, Holzmüller V, Grimbacher B, Michonneau D, Andrieux G, Socié G, Kolter J, Börries M, Follo M, Blaeschke F Sevenich L, Prinz M, Zeiser R, Vinnakota JM: AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling. Blood Adv; doi: 10.1182/bloodadvances.2024015000 (2025).

Schaible P, Henschel J, Erny D: How the gut microbiota impacts neurodegenerative diseases by modulating CNS immune cells.
J Neuroinflammation 22(1):60; doi: 10.1186/s12974-025-03371-0 (2025).

Saller BS, Wöhrle S, Fischer L, …, Schwemmle M, Groß CJ, Groß O: Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation. Immunity; doi: 10.1016/j.immuni.2024.10.012 (2024).

Giesler S, Riemer R, Lowinus T, Zeiser R: Immune-mediated colitis after immune checkpoint inhibitor therapy . Trends Mol Med S1471-4914(24)00266-1; doi: 10.1016/j.molmed.2024.09.009 (2024).

Nath S, Martínez Santamaría JC, Chu Y-H, Choi JS, Conforti P, Lin J-D, Sankowski R, Amann L, Galanis C, Wu K, Deshpande SS, Vlachos A, Prinz M, Lee JK, Schachtrup C: Interaction between subventricular zone microglia and neural stem cells impacts the neurogenic response in a mouse model of cortical ischemic stroke. Nat Commun 15:9095. doi: 10.1038/s41467-024-53217-1 (2024).

Bøstrand SMK, Seeker LA, Bestard-Cuche N, Kazakou N-L, Jäkel S, Kenkhuis B,
Henderson NC, de Bot ST, van Roon-Mom WMC, Priller J and Williams A: Mapping the glial transcriptome in Huntington’s disease using snRNAseq: selective disruption of glial signatures across brain regions. Acta Neuropathol Commun 12:165; doi: 10.1186/s40478-024-01871-3 (2024).

Dumas AA, Gasull AD, Prinz M: Beyond borders: the choroid plexus-immune communication during neuroinflammation. Signal Transduct Target Ther 9:278. doi: 10.1038/s41392-024-01997-9 (2024).

Hasavci D, Blank T: A microglial compliment: controlling neuronal function from within. Signal Transduct Target Ther 9(1):267; doi: 10.1038/s41392-024-01989-9 (2024).

Schmidt D, Endres C, Hoefflin R, Andrieux G, Zwick M, Karantzelis N, Staehle HF, Vinnakota JM, Duquesne S, Mozaffari Jovein M, Pfeifer D, Becker H, Blazar BR, Zähringer A, Duyster J, Brummer T, Boerries M, Baumeister J, Shoumariyeh K, Li J, Green AR, Heidel FH, Tirosh I, Pahl HL, Leimkühler N, Köhler N, de Toledo MAS, Koschmieder S, Zeiser R: Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment. Cancer Res 84(18):2985-3003; doi: 10.1158/0008-5472.CAN-23-3553 (2024).

Früholz I, Meyer-Luehmann M: The intricate interplay between microglia and adult neurogenesis in Alzheimer’s disease . Front Cell Neurosci 18:1456253; doi: 10.3389/fncel.2024.1456253 (2024).

Lisowski P, Lickfett S, Rybak-Wolf A, Menacho C, Le S, Pentimalli TM, Notopoulou S, Dykstra W, Oehler D, López-Calcerrada S, Mlody B, Otto M, Wu M, Richter Y, Roth P, Anand R, Kulka LAM, Meierhofer D, Glazar P, Legnini I, Telugu NS, Hahn T, Neuendorf N, Miller DC, Böddrich A, Polzin A, Mayatepek E, Diecke S, Olzscha H, Kirstein J, Ugalde C, Petrakis S, Cambridge S, Rajewsky N, Kühn R, Wanker EE, Priller J, Metzger JJ & Prigione A: Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure. Nat Commun 15:7027. doi: 10.1038/s41467-024-51216-w (2024).

Wogram E, Sümpelmann F, Dong W, Rawat E, Fernández Maestre I, Fu D, Braswell B, Khalil A, Buescher JM, Mittler G, Borner GHH, Vlachos A, Tholen S, Schilling O, Bell GW, Rambold AS, Akhtar A, Schnell O, Beck J, Abu-Remaileh M, Prinz M, Jaenisch R: Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes. Immunity; doi:https://doi.org/10.1016/j.immuni.2024.07.019 (2024).