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Chotima Böttcher, Stephan Schlickeiser, Marjolein A. M. Sneeboer, Desiree Kunkel, Anniki Knop, Evdokia Paza, Pawel Fidzinski, Larissa Kraus, Gijsje J. L. Snijders, René S Kahn, Axel R Schulz, Henrik E Mei, NBB-Psy, Elly M. Hol, Britta Siegmund, Rainer Glauben, Eike J Spruth, Lot D de Witte & Josef Priller: Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry, Nature Neuroscience 22, 78–90 (2019).

 

Anat Shemer, Jonathan Grozovski, Tuan Leng Tay, Jenhan Tao, Alon Volaski, Patrick Süß, Alberto Ardura-Fabregat, Mor Gross-Vered, Jung-Seok Kim, Eyal David, Louise Chappell-Maor, Lars Thielecke, Christopher K. Glass, Kerstin Cornils, Marco Prinz & Steffen Jung: Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge, Nature Communications 9, 5206 (2018).

Fabrizio Costa, Dominic Grün, and Rolf Backofen: GraphDDP: a graph-embedding approach to detect differentiation pathways in single-cell-data using prior class knowledge, Nature Communications 9, 3685 (2018).

Derkow K, Rössling R, Schipke C, Krüger C, Bauer J, Fähling M, Stroux A, Schott E, Ruprecht K, Peters O, and Lehnardt S: Distinct expression of the neurotoxic microRNA family let-7 in the cerebrospinal fluid of patients with Alzheimer’s disease, PLoS One. 13(7):e0200602 (2018).

Zhana Haimon, Alon Volaski, Johannes Orthgiess, Sigalit Boura-Halfon, Diana Varol, Anat Shemer, Simon Yona, Binyamin Zuckerman, Eyal David, Louise Chappell-Maor, Ingo Bechmann, Martin Gericke, Igor Ulitsky and Steffen Jung: Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies, Nature Immunology 19, 636–644 (2018).

Jan Hülsdünker, Katja J. Ottmüller, Hannes P. Neeff, Motoko Koyama, Zhan Gao, Oliver S. Thomas, Marie Follo, Ali Al-Ahmad,
Gabriele Prinz, Sandra Duquesne, Heide Dierbach, Susanne Kirschnek, Tim Lämmermann, Martin J. Blaser, Brian T. Fife,
Bruce R. Blazar, Andreas Beilhack, Geoffrey R. Hill, Georg Häcker, and Robert Zeiser, Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset, blood 131 (16), 1858-1869 (2018).

Stefanie Kälin, Kelly R. Miller, Roland E. Kälin, Marina Jendrach, Christian Witzel, and Frank Heppner: CNS myeloid cells critically regulate heat hyperalgesia, J. Clin. Invest. (2018) https://doi.org/10.1172/JCI95305.

Mathew NR, Baumgartner F, Braun L, O’Sullivan D, Thomas S, Waterhouse M, Müller TA, Hanke K, Taromi S, Apostolova P, Illert AL, Melchinger W, Duquesne S, Schmitt-Graeff A, Osswald L, Yan KL, Weber A, Tugues S, Spath S, Pfeifer D, Follo M, Claus R, Lübbert M, Rummelt C, Bertz H, Wäsch R, Haag J, Schmidts A, Schultheiss M, Bettinger D, Thimme R, Ullrich E, Tanriver Y, Vuong GL, Arnold R, Hemmati P, Wolf D, Ditschkowski M, Jilg C, Wilhelm K, Leiber C, Gerull S, Halter J, Lengerke C, Pabst T, Schroeder T, Kobbe G, Rösler W, Doostkam S, Meckel S, Stabla K, Metzelder SK, Halbach S, Brummer T, Hu Z, Dengjel J, Hackanson B, Schmid C, Holtick U, Scheid C, Spyridonidis A, Stölzel F, Ordemann R, Müller LP, Sicre-de-Fontbrune F, Ihorst G, Kuball J, Ehlert JE, Feger D, Wagner EM, Cahn JY, Schnell J, Kuchenbauer F, Bunjes D, Chakraverty R, Richardson S, Gill S, Kröger N, Ayuk F, Vago L, Ciceri F, Müller AM, Kondo T, Teshima T, Klaeger S, Kuster B, Kim DDH, Weisdorf D, van der Velden W, Dörfel D, Bethge W, Hilgendorf I, Hochhaus A, Andrieux G, Börries M, Busch H, Magenau J, Reddy P, Labopin M, Antin JH, Henden AS, Hill GR, Kennedy GA, Bar M, Sarma A, McLornan D, Mufti G, Oran B, Rezvani K, Shah O, Negrin RS, Nagler A, Prinz M, Burchert A, Neubauer A, Beelen D, Mackensen A, von Bubnoff N, Herr W, Becher B, Socié G, Caligiuri MA, Ruggiero E, Bonini C, Häcker G, Duyster J, Finke J, Pearce E, Blazar BR, and Zeiser R.: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells, Nat Med. 24(3), 282-291 (2018).

Prestipino A, Emhardt AJ, Aumann K, O’Sullivan D, Gorantla SP, Duquesne S, Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, Veratti P, Hettich M, Niedermann G, Bartholomä M, Shoumariyeh K, Jutzi JS, Wehrle J, Dierks C, Becker H, Schmitt-Graeff A, Follo M, Pfeifer D, Rohr J, Fuchs S, Ehl S, Hartl FA, Minguet S, Miething C, Heidel FH, Kröger N, Triviai I, Brummer T, Finke J, Illert AL, Ruggiero E, Bonini C, Duyster J, Pahl HL, Lane SW, Hill GR, Blazar BR, von Bubnoff N, Pearce EL, Zeiser R, Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms, Sci Transl Med. 10 (429), eaam7729 (2018).